In recent debate over the FDA's approval of the Alzheimer's drug aducanumab, we've heard a lot about the "amyloid hypothesis." In that context, it's refreshing to learn about a model of Alzheimer's neurodegeneration that ...
Jun 29, 2021
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Researchers at the University of Cincinnati say a regulatory protein found in skeletal muscle fiber may play an important role in the body's fight or flight response when encountering stressful situations.
Apr 23, 2021
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Atherosclerosis is the result of a buildup of lipids in the inner walls of blood vessels, and is a major cause of heart disease and stroke. In a new study, researchers from the University of Tsukuba discovered a novel role ...
Dec 21, 2020
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An unexplored kinase in heart muscle cells may be a good target to treat heart failure, a disease that is only incrementally delayed by existing therapies. Failing human hearts showed reduced amounts of this kinase, and preclinical ...
Oct 31, 2019
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Inherited diseases of the eye account for at least 2 million cases of blindness worldwide. A few hundred genes that cause eye disease have been identified, but in many cases the cause is unknown because not all eye disease ...
Feb 20, 2019
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一个来自母亲的基因ys such a crucial role in the development of the placenta that its dysfunction leads to miscarriages. Researchers from the Medical Faculty of Ruhr-Universität Bochum (RUB) have observed this ...
Oct 19, 2018
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Researchers have shown that when parts of a genome known as enhancers are missing, the heart works abnormally, a finding that bolsters the importance of DNA segments once considered "junk" because they do not code for specific ...
Oct 5, 2016
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Infertility affects about 15 percent of couples around the world. A couple's fertility depends on both the female's and male's ability to reproduce, which relies on thousands of genes working properly. In the male mouse, ...
Jun 27, 2016
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常用的纯系小鼠克雷亚tion of so-called knockout animals has been found to carry a previously undetected mutation that could affect the results of immune system research studies. In paper receiving ...
May 19, 2016
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The average number of eggs for genetically modified mice (knockout mice) obtained using previous methods of superovulation induction is about 20 but in reality the number is often much smaller, about 10 or less. However, ...
Jun 19, 2015
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