Immunology

Engineered bacteria find tumors, then alert immune cells

Combining discoveries in cancer immunology with sophisticated genetic engineering, Columbia University researchers have created a sort of "bacterial suicide squad" that targets tumors, attracting the host's own immune cells ...

Oncology & Cancer

Exercise has a direct role in fighting breast cancer

While it is generally accepted that exercise can benefit a person's overall health, a recently published paper has found a direct link between muscle contraction and a reduction in breast cancer.

Oncology & Cancer

Differences in animal biology can affect cancer drug development

A small but significant metabolic difference between human and mouse lung tumor cells, has been discovered by Weill Cornell Medicine researchers, explaining a discrepancy in previous study results, and pointing toward new ...

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Transforming growth factor

Transforming growth factor(sometimes referred to asTumor growth factor, orTGF) is used to describe two classes of polypeptide growth factors, TGFα and TGFβ.

The name "Transforming Growth Factor" is somewhat arbitrary, since the two classes of TGFs are not structurally or genetically related to one another, and they act through different receptor mechanisms. Furthermore, they do not always induce cellular transformation, and are not the only growth factors that induce cellular transformation.

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