A single drug compound simultaneously attacks hard-to-treat prostate cancer on several fronts, according to a new study in mice and human cells. It triggers immune cells to attack, helps the immune cells penetrate the tumor, ...
Nov 23, 2022
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新的研究在临床《美国年代ociety of Nephrology highlights the potential to lower the burden of chronic kidney disease (CKD) complications by delaying or even preventing kidney failure and premature ...
Nov 22, 2022
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Northwestern Medicine scientists have discovered the pathways through which autoantibodies—immune proteins that mistakenly attack a person's own body—leak out of blood vessels and cause primary graft dysfunction in some ...
Nov 18, 2022
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Autism spectrum disorder (ASD) refers to a group of disabilities due to atypical brain development. Individuals with ASD have difficulties in social communication and interaction. Diverse causes of ASD are hypothesized, but ...
Nov 17, 2022
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Two studies published by The BMJ today provide up to date evidence on the effectiveness of both currently licensed and possible COVID-19 treatments under everyday ("real world") conditions, helping to shed more light on whether ...
Nov 16, 2022
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The multilevel Julich Brain Atlas developed by researchers in the Human Brain Project (HBP) could help with studies of psychiatric and aging disorders by correlating brain networks with their underlying anatomical structure. ...
2022年11月15日
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In recent years, genetically re-engineered immune cells—armed with molecular weaponry to recognize and destroy tumor cells—have changed the landscape of cancer treatment. Now, UC San Francisco researchers have developed ...
Nov 10, 2022
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For the first time, scientists have used CRISPR technology to insert genes that allow immune cells to focus their attack on cancer cells, potentially leaving normal cells unharmed and increasing the effectiveness of immunotherapy. ...
Nov 10, 2022
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Parkinson's disease affects 3% of population over 65 years old, and the average age of onset is 60. In juvenile Parkinson's, which accounts for 5–10% of Parkinson's cases, the disease begins before 40 years old.
Nov 08, 2022
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New images from scientists at Cold Spring Harbor Laboratory (CSHL) reveal for the first time the three-dimensional structures of a set of molecules critical for healthy brain function.
Nov 02, 2022
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In biochemistry, areceptoris a protein molecule, embedded in either the plasma membrane or cytoplasm of a cell, to which a mobile signaling (or "signal") molecule may attach. A molecule which binds to a receptor is called a "ligand," and may be a peptide (such as a neurotransmitter), a hormone, a pharmaceutical drug, or a toxin, and when such binding occurs, the receptor undergoes a conformational change which ordinarily initiates a cellular response. However, some ligands merely block receptors without inducing any response (e.g. antagonists). Ligand-induced changes in receptors result in physiological changes which constitute the biological activity of the ligands.
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