Psychology & Psychiatry

Viral infections during pregnancy affect maternal care behavior

Viral infections during pregnancy affect the mother's brain and her postpartum care behavior. These are the findings of a research study in a mouse model conducted at MedUni Vienna. The results were published in the leading ...

Addiction

More nuance in liquor licensing can serve public health

A new toolkit that provides data on alcohol-related harm and licensed premises helps new liquor license applications be considered within their local health context, a UNSW alcohol policy researcher says.

Neuroscience

Researchers discover how hormones define brain sex differences

Sex hormones play an important role in shaping an animal's behavior, and their influence starts early. Early-life hormonal surges help shape the developing brain, establishing circuitry that will influence behavior for a ...

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孩子没有尿布睡眠不佳,研究说

Children whose parents cannot afford diapers do not get quality sleep, according to a study by the Rutgers School of Nursing.

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Neural development

The study ofneural developmentdraws on both neuroscience and developmental biology to describe the cellular and molecular mechanisms by which complex nervous systems emerge during embryonic development and throughout life.

Some landmarks of embryonic neural development include the birth and differentiation of neurons from stem cell precursors, the migration of immature neurons from their birthplaces in the embryo to their final positions, outgrowth of axons from neurons and guidance of the motile growth cone through the embryo towards postsynaptic partners, the generation of synapses between these axons and their postsynaptic partners, and finally the lifelong changes in synapses which are thought to underlie learning and memory.

通常,这些神经发育过程be broadly divided into two classes: activity-independent mechanisms and activity-dependent mechanisms. Activity-independent mechanisms are generally believed to occur as hardwired processes determined by genetic programs played out within individual neurons. These include differentiation, migration and axon guidance to their initial target areas. These processes are thought of as being independent of neural activity and sensory experience. Once axons reach their target areas, activity-dependent mechanisms come into play. Neural activity and sensory experience will mediate formation of new synapses, as well as synaptic plasticity, which will be responsible for refinement of the nascent neural circuits.

Developmental neuroscience uses a variety of animal models including miceMus musculus, the fruit flyDrosophila melanogaster, the zebrafishDanio rerio,Xenopus laevistadpoles and the wormCaenorhabditis elegans, among others.

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