RA患者将贸易效果较少,缩短治疗
(健康日)基于假设情景,类风湿性关节炎(RA)患者将接受疗效较低,风险较低的治疗,以实现较低的持续时间和频率,据7月份发表于7月份问题关节炎护理与研究。
Christine Poulos, Ph.D., from RTI Solutions in Research Triangle Park, N.C., and colleagues surveyed 901 patients with a self-reported physician diagnosis of moderate to severe RA regarding hypothetical treatment choices (396 in an online panel and 505 as part of the RA Information, Service, and Education group). Relative importances were estimated for six attributes included in all treatment choices: response rate, mode of administration, treatment duration, treatment frequency, and the risks of immediate mild and serious treatment reactions.
研究人员发现,治疗特征变化的边际效用最大,用于治疗持续时间的一小时变化,而每年治疗频率的单位变化是第二个最重要的变化。对于年治疗频率,变化的边际效用取决于治疗持续时间,反之亦然。
作者写道,“受访者将接受效率较低和更大风险的治疗,以实现较低的持续时间和频率。”“以前的研究将患者偏好与治疗依从性有关,表明持续时间或频率的减少可以改善依从性和健康结果。”
一个提交人是Genentech的员工,赞助了这项研究。
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