Wear and tear on joints can lead to inflammation, breakdown of cartilage and development of osteoarthritis. Scientists at UF Scripps Biomedical Research have found a possible new target to fight this painful cascade.
Oct 14, 2022
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Breast cancer is categorized into three major subtypes: hormone receptor-positive, HER2-positive, and triple-negative. Although there are targeted therapeutic approaches for the first two, there are limited options for triple ...
Aug 29, 2022
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The Center for Nuclear Receptors and Cell Signaling at the University of Houston has developed a new way to detect very rare and highly heterogeneous circulating tumor cells with high specificity and sensitivity. The UniPro ...
Apr 13, 2022
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Women have many choices for birth control, ranging from pills to patches to intrauterine devices, and partly as a result, they bear most of the burden of preventing pregnancy. But men's birth control options—and, therefore, ...
Mar 23, 2022
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A molecule known as anaplastic lymphoma kinase (ALK) is a driver of several cancers, including pediatric neuroblastoma, B-cell lymphomas, and myofibroblast tumors. But for years much about this molecule—its role in the ...
Nov 26, 2021
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ALK is a receptor tyrosine kinase that regulates important functions in the central nervous system. Scientists at St. Jude Children's Research Hospital have used leading-edge structural biology techniques to reveal in more ...
Nov 24, 2021
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A research team at the University of Oulu, Finland, has discovered a new mechanism in cells that causes an increase in harmful LDL cholesterol. The observation made by the researchers may explain the adverse effects of certain ...
May 18, 2021
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一个小组Centro Nacional de Investigaciones Cardiovasculares (CNIC), working in partnership with researchers at Mount Sinai Hospital in New York, has discovered a new molecular mechanism mediated by nuclear receptors ...
Apr 3, 2020
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An industrial chemical—phased out since 2002, but previously used in stain and water-repellent products and firefighting foam—alters the gut microbiome of mice and could have implications for human health, according to ...
Jan 22, 2020
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A single cholesterol-derived molecule, called 27-hydroxycholesterol (27HC), lurks inside your bloodstream and will increase your body fat, even if you don't eat a diet filled with red meat and fried food. That kind of diet, ...
Aug 28, 2019
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