Breast implants after mastectomy associated with very low risk of lymphoma

breast cancer
Credit: Unsplash/CC0 Public Domain

The incidence of a rare cancer, anaplastic large-cell lymphoma (ALCL), has surged in recent years, possibly because of the growing use of textured breast implants. Considering this trend, some breast cancer patients who undergo mastectomy may wonder if the benefits of getting reconstructive implants are worth the risk of developing a second cancer.

A new Columbia study should make many women's decisions easier. The study found that the risk of developing ALCL after reconstructive surgery is extremely low: Each year, about 12 cases are expected to occur per 1 million women who've had.

"The risk of developing ALCL is actually much lower than the risk of experiencing a relapse of," says lead author Connor J. Kinslow, MD, a resident in radiation oncology at the Columbia University Vagelos College of Physicians and Surgeons.

"Based on our findings, we do not believe that women should be dissuaded from having implant-based breast reconstruction after mastectomy solely due to the risk of ALCL."

The new study was designed to provide women with accurate information about risk and is the first to look at rates of ALCL in breast cancer survivors who've had breast implants after mastectomy.

The researchers used a national cancer registry to identify 57,000 women who had undergone mastectomy with implant reconstruction for breast cancer or乳腺癌原位(一个早期的、非侵入性的阶段cer) between 2000 and 2018. The median follow-up time was seven years, and roughly 16,000 women were followed for at least 10 years.

Though the study found that women who have had post-mastectomydo have a higher risk of ALCL than women in general (each year, 0.3 cases are expected per million in the), "it should be noted that ALCL is a rare cancer," says study leader David Horowitz, MD, assistant professor ofat Columbia University Vagelos College of Physicians and Surgeons. "Among the 57,000 women in the study, only five cases of ALCL were diagnosed over the combined 421,000 years of follow-up."

"Women who have had one cancer are understandably nervous about having a second," Kinslow says. "But that shouldn't necessarily put them off from having reconstructive implants. For many women, breast reconstruction after mastectomy is extremely important to quality of life, and women should feel comfortable going ahead with implants without adding to the psychological burdens that come with a breast cancer diagnosis."

The work is published in the journalJAMA Network Open.

更多的信息:Connor J. Kinslow et al, Risk of Anaplastic Large Cell Lymphoma Following Postmastectomy Implant Reconstruction in Women With Breast Cancer and Ductal Carcinoma in Situ,JAMA Network Open(2022).DOI: 10.1001/jamanetworkopen.2022.43396
Journal information: JAMA Network Open

Citation: Breast implants after mastectomy associated with very low risk of lymphoma (2022, December 2) retrieved 5 December 2022 from //www.puressens.com/news/2022-12-breast-implants-mastectomy-lymphoma.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.

Explore further

Cases of anaplastic large-cell lymphoma of breast up in U.S. women

36shares

Feedback to editors